Catalog Number: RK42015-010: For 50-100 IHC Tests with frozen or FFPE tissues
Package Size: RK42015-005: For 25-50 IHC Tests with frozen or FFPE tissues
Concentration: Ready to use
Storage: Store at 4°C upon receiving. DO NOT FREEZE.
Intended Use: For Research Use Only. This product is designed and developed to meet the need for ultra-fast immunohistochemistry (IHC) testing at convenient room temperature. The assay is optimized to work on frozen tissue sections using a 10 minute IHC protocol.
Introduction: The key component in this kit is horseradish peroxidase (HRP) polymer (PolyHRP) labeled Rabbit anti-human cytokeratin type 7 (CK7) monoclonal antibody clone R284. The product has been developed using Novodiax’s proprietary enzyme polymerization technology and Direct IHC technology called ihcDirect (Patent Pending) and is optimized for frozen tissues. The incubation time on frozen tissues is 3 minute and on FFPE tissues 15-30 minutes. CK7 is often used together with CK20. A combination of CK7+/CK20+ has been observed in carcinomas of bile duct (extrahepatic/gallbladder), pancreas, urothelium, primary mucinous tumors of ovary (74%), upper GI tract (78%) and endocervix (88%); CK7+/CK20- in carcinomas of bile duct (intrahepatic), breast, endocervical and endometrial adenocarcinoma, esophagus, lung (not mucinous bronchioloalveolar), salivary gland, thyroid, and mesothelioma; CK7-/CK20+ in carcinoma of colon (particularly early stage), primary mucinous tumors of lower GI tract (79%), bladder adenocarcinoma (29%); CK7-/CK20- in carcinoma of adrenal cortex, prostate.
ihcDirect® CK7 (Rabbit monoclonal antibody Clone R284)
- Catalog Number: RK42015
- Availability: In Stock
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