Catalog Number: RK41038-R010: For 50-100 IHC Tests with frozen or FFPE tissues
Package Size: RK41038-R005: For 25-50 IHC Tests with frozen or FFPE tissues
Concentration: Ready to use
Storage: Store at 4°C upon receiving. DO NOT FREEZE.
Intended Use: For Research Use Only. This product is designed and developed to meet the need for ultra-fast immunohistochemistry (IHC) testing at convenient room temperature. The assay is optimized to work on frozen tissue sections using a 10 minute IHC protocol.
Introduction: The key component in this kit is horseradish peroxidase (HRP) polymer (PolyHRP) labeled mouse anti-human carcinoembryonic antigen (CEA, also known as CD66e) monoclonal antibody clone C135. The product has been developed using Novodiax’s proprietary enzyme polymerization technology and Direct IHC technology called ihcDirect (Patent Pending) and is optimized for frozen tissues. The incubation time on frozen tissues is 3 minute and on FFPE tissues 15-30 minutes. CEA is often detected in glycocalyx of fetal epithelial cells, may play a role in the metastasis of cancer cells and usually considered an epithelial marker with strong staining in adenocarcinomas. CEA has been used to distinguish adenocarcinoma (lung) vs. epithelioid mesothelioma with a 97% specific for lung adenocarcinoma, negative for mesothelioma; if in fluid cytology, 76% of lung adenocarcinoma is positive. High level of CEA are suggestive of malignant breast cancer, not benign breast disease in FNA fluid.
ihcDirect® CEA (Mouse monoclonal antibody Clone C135)
- Catalog Number: RK41038
- Availability: In Stock
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