• ihcDirect® CK 8/18 (Mouse monoclonal antibody Clone C94)

Catalog Number:    RK41001-010: For 50-100 IHC Tests with frozen or FFPE tissues 
Package Size:           RK41001-005: For 25-50 IHC Tests with frozen or FFPE tissues
Concentration:        Ready to use
Specificity:                Cytokeratins 8 and 18
Species Reactivity: Human
Storage:                     4°C upon receiving. Do not freeze.
Intended Use:          For Research Use Only. This product is designed and developed to meet the need for ultra-fast immunohistochemistry (IHC) testing at convenient room temperature. The assay is optimized to work on frozen tissue sections using a 10 minute IHC protocol.

Introduction:            The key component in this kit is horseradish peroxidase (HRP) polymer (PolyHRP) labeled mouse anti-human cytokeratin 8/18 antibody (clones C94). The product has developed based on using Novodiax’s proprietary enzyme polymerization technology and Direct IHC technology called ihcDirect (Patent Pending) and is optimized for IHC on frozen tissues. The incubation time on frozen tissues is 3 minutes and on FFPE tissues 15-30 minutes.

Monoclonal antibody clone 94 reacts with human cytokeratin intermediate low molecular weight filament proteins of 52.5 kD and 45 kD, i.e., cytokeratins 8 and 18, respectively. Cytokeratins 8 and 18 are expressed in most simple and glandular epithelium, such as thyroid, female breast, gastrointestinal tract, and respiratory tract. In cancer tissues, adenocarcinomas and most non-keratinizing squamous carcinomas express these proteins, but keratinizing squamous carcinomas do not. Antibodies to CK8 and CK18 may be utilized in the classification of tumors of epithelial origin.

ihcDirect® CK 8/18 (Mouse monoclonal antibody Clone C94)

  • Catalog Number: RK41001
  • Availability: In Stock
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