ihcDirect® TROP2 (calcium signal transducer 2) is a polyHRP conjugated rabbit monoclonal antibody (clone R1011). TROP2 is a 35 kDa transmembrane glycoprotein and functions as an intracellular calcium signal transducer. It promotes cell regeneration, proliferation, invasion and survival in normal tissues. TROP2 mutations may result in gelatinous drop-like corneal dystrophy and it can be overexpressed in carcinomas which may promote increased tumor aggressiveness and metastasis. TROP2 may be found in colorectal, gastric and pancreatic cancers, squamous cell cancers of the oral cavity, non–small cell cancers of the lung, as well as endometrial and ovarian malignancies.
TROP2 Ab
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Description
Additional information
| Weight | 1 oz |
|---|---|
| Dimensions | 1 × 1 × 2 in |
| Applications | Immunohistochemistry (IHC) |
| Intended Use | In Vitro Diagnostic (IVD) for Laboratory Use |
| Antigen | Trophoblast cell-surface antigen 2 |
| Antibody Type | Primary Antibody, Monoclonal |
| Species Reactivity | Rabbit Anti-Human |
| Concentration | Ready to use |
| Storage | Store at 2-8°C. Do not freeze. |
| Quantity | 300 IHC Tests with frozen or FFPE tissues, 150 IHC Tests with frozen or FFPE tissues, 100 IHC Tests with frozen or FFPE tissues, 50 IHC Tests with frozen or FFPE tissues |
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